Volasertib
Product Specifications
CAS Number
755038-65-4
Target
Apoptosis, PLK
Related Pathways
Apoptosis, Cell Cycle/Checkpoint
Purity
0.9972
Bioactivity
Volasertib (BI 6727) (BI-6727) is a potent inhibitor of PLK1 (IC50: 0.87 nM), inducing mitotic arrest and apoptosis. It also inhibits PLK2/PLK3 (IC50s: 5/56 nM) .
Smiles
CC[C@H]1N(C(C)C)c2nc(Nc3ccc(cc3OC)C(=O)N[C@H]3CC[C@@H](CC3)N3CCN(CC4CC4)CC3)ncc2N(C)C1=O
Molecular Formula
C34H50N8O3
Molecular Weight
618.81
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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