PBRM1-BD2-IN-8

Product Specifications

CAS Number

2819989-75-6

Target

Epigenetic Reader Domain

Related Pathways

Chromatin/Epigenetic

Purity

0.9989

Bioactivity

PBRM1-BD2-IN-8 (compound 34) is a potent PBRM1 Bromodomain inhibitor with PBRM1-BD2 Kd of 4.4 ?M, PBRM1-BD2 IC50 of 0.16 ?M, and PBRM1-BD5 Kd of 25 ?M; PBRM1-BD2-IN-8 shows anti-cancer activity.

Smiles

O=C1C=2C(NC(N1)C3=CC(C)=CC=C3)=CC=CC2Br

Molecular Formula

C15H13BrN2O

Molecular Weight

317.18

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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