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PBRM1-BD2-IN-2

Product Specifications

CAS Number

2819989-57-4

Target

Epigenetic Reader Domain

Related Pathways

Chromatin/Epigenetic

Purity

>99.99%

Bioactivity

PBRM1-BD2-IN-2, a selective and cell-active inhibitor of the polybromo-1 (PBRM1) bromodomain, exhibits binding affinity and inhibitory activity specifically targeting the PBRM1-BD2 domain, with Kd and IC50 values of 9.3 μM and 1.0 μM, respectively. This compound is utilized in cancer research.

Smiles

O=C1C=2C(NC(N1)C3=C(Cl)C=CC=C3F)=CC=CC2Cl

Molecular Formula

C14H9Cl2FN2O

Molecular Weight

311.14

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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