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USP5-IN-1

Product Specifications

Target

DUB

Related Pathways

Ubiquitination, Cell Cycle/Checkpoint, DNA Damage/DNA Repair

Purity

0.9976

Bioactivity

USP5-IN-1 (compound 64) is a potent deubiquitinase USP5 inhibitor that binds to the USP5 ZnF-UBD with a KD of 2.8 μM and is selective over nine proteins containing structurally similar ZnF-UBD domains. Additionally, USP5-IN-1 inhibits the USP5 catalytic cleavage of a di-ubiquitin substrate [1].

Smiles

O=C(O)CNC(=O)C1=CC=C(S(=O)(=O)N2CCC(C3=CC=C(Cl)C=C3)CC2)C=N1

Molecular Formula

C19H20ClN3O5S

Molecular Weight

437.9

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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