MSC2504877
Product Specifications
CAS Number
1460286-21-8
Target
PARP, Others
Related Pathways
DNA Damage/DNA Repair, Chromatin/Epigenetic, Others
Purity
0.9972
Bioactivity
MSC2504877 is an inhibitor of tankyrase and enhances the effects of clinical CDK4/6 inhibitors. MSC2504877 suppresses the upregulation of Cyclin D2 and Cyclin E2 caused by palbociclib and enhances the suppression of phospho-Rb.
Smiles
Cc1ccc2n1cc([nH]c2=O)-c1ccc(cc1)C(C)(C)O
Molecular Formula
C17H18N2O2
Molecular Weight
282.34
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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