CFT7455
Product Specifications
CAS Number
2504235-67-8
Target
Ligand for E3 Ligase, IKZF, Molecular Glues
Related Pathways
Immunology/Inflammation, PROTAC
Purity
0.9793
Bioactivity
CFT7455 (Cemsidomide) is an anti-cancer agent showing high affinity to the cereblon E3 ligase with a Kd of 0.9 nM. CFT7455 is an orally active degrader of zinc finger transcription factors Ikaros (IKZF1), and Aiolos (IKZF3) .
Smiles
[H][C@@]1(CCC(=O)NC1=O)N1C(=O)c2cccc3c(Cc4ccc(CN5CCOCC5)cc4)ccc1c23
Molecular Formula
C28H27N3O4
Molecular Weight
469.53
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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