CFT7455

Product Specifications

CAS Number

2504235-67-8

Target

Ligand for E3 Ligase|||IKZF|||Molecular Glues

Related Pathways

Immunology/Inflammation|||PROTAC

Purity

0.9793

Bioactivity

CFT7455 (Cemsidomide) is an anti-cancer agent showing high affinity to the cereblon E3 ligase with a Kd of 0.9 nM. CFT7455 is an orally active degrader of zinc finger transcription factors Ikaros (IKZF1), and Aiolos (IKZF3) .

Smiles

[H][C@@]1(CCC(=O)NC1=O)N1C(=O)c2cccc3c(Cc4ccc(CN5CCOCC5)cc4)ccc1c23

Molecular Formula

C28H27N3O4

Molecular Weight

469.53

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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