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YS-370

Product Specifications

CAS Number

2470908-79-1

Target

P-gp

Related Pathways

Neuroscience, Membrane transporter/Ion channel

Purity

0.98055

Bioactivity

YS-370 is an orally active inhibitor of P-gp and shows moderate inhibition against CYP3A4. YS-370 effectively reverses multidrug resistance to paclitaxel and colchicine and exhibits stronger antitumor activity in combination with paclitaxel.

Smiles

COc1cc2ncnc(-c3c(-c4ccccc4)n(Cc4ccccc4Br)c4ccccc34)c2cc1OCCCN1CCOCC1

Molecular Formula

C37H35BrN4O3

Molecular Weight

663.6

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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