YS-370
Product Specifications
CAS Number
2470908-79-1
Target
P-gp
Related Pathways
Neuroscience, Membrane transporter/Ion channel
Purity
0.98055
Bioactivity
YS-370 is an orally active inhibitor of P-gp and shows moderate inhibition against CYP3A4. YS-370 effectively reverses multidrug resistance to paclitaxel and colchicine and exhibits stronger antitumor activity in combination with paclitaxel.
Smiles
COc1cc2ncnc(-c3c(-c4ccccc4)n(Cc4ccccc4Br)c4ccccc34)c2cc1OCCCN1CCOCC1
Molecular Formula
C37H35BrN4O3
Molecular Weight
663.6
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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