VP3.15 dihydrobromide
Product Specifications
CAS Number
1281681-33-1
Target
PDE|||GSK-3
Related Pathways
PI3K/Akt/mTOR signaling|||Stem Cells|||Metabolism
Purity
0.9967
Bioactivity
VP3.15 dihydrobromide is a potent, orally bioavailable, and CNS-penetrant dual inhibitor of phosphodiesterase (PDE7) and glycogen synthase kinase (GSK) 3, with IC50 values of 1.59 ?M and 0.88 ?M, respectively.
Smiles
Br.Br.C(CN1CCOCC1)\N=c1 c(-c2ccccc2)n(s1)-c1ccccc1
Molecular Formula
C20H24Br2N4OS
Molecular Weight
528.3
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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