Rubitecan
Product Specifications
CAS Number
91421-42-0
Target
Topoisomerase
Related Pathways
DNA Damage/DNA Repair
Purity
0.98
Bioactivity
Rubitecan (9-Nitrocamptothecin) is a DNA topoisomerase I inhibitor. It inhibits DNA topoisomerase I and increases the fraction of supercoiled DNA in a cell-free assay in a concentration-dependent manner.Rubitecan is a semisynthetic agent related to camptothecin with potent antitumor and antiviral properties.
Smiles
CC[C@@]1(O)C(=O)OCc2c1cc1-c3nc4cccc([N+]([O-])=O)c4cc3Cn1c2=O
Molecular Formula
C20H15N3O6
Molecular Weight
393.35
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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