Rigosertib sodium

Product Specifications

CAS Number

592542-60-4

Target

Apoptosis, PLK, PI3K

Related Pathways

Apoptosis, PI3K/Akt/mTOR signaling, Cell Cycle/Checkpoint

Purity

0.9937

Bioactivity

Rigosertib sodium (ON-01910), a non-ATP-competitive inhibitor of PLK1 (IC50=9 nM), exhibits 30-fold higher specificity activity over Plk2 and no effect on Plk3.

Smiles

COc1c(cc(cc1)CS(=O)(=O)/C=C/c1c(cc(cc1OC)OC)OC)NCC(=O)[O-].[Na+]

Molecular Formula

C21H24NNaO8S

Molecular Weight

473.47

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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