Rigosertib sodium
Product Specifications
CAS Number
592542-60-4
Target
Apoptosis, PLK, PI3K
Related Pathways
Apoptosis, PI3K/Akt/mTOR signaling, Cell Cycle/Checkpoint
Purity
0.9937
Bioactivity
Rigosertib sodium (ON-01910), a non-ATP-competitive inhibitor of PLK1 (IC50=9 nM), exhibits 30-fold higher specificity activity over Plk2 and no effect on Plk3.
Smiles
COc1c(cc(cc1)CS(=O)(=O)/C=C/c1c(cc(cc1OC)OC)OC)NCC(=O)[O-].[Na+]
Molecular Formula
C21H24NNaO8S
Molecular Weight
473.47
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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