Belvarafenib

Product Specifications

CAS Number

1446113-23-0

Target

Raf

Related Pathways

MAPK

Purity

0.9965

Bioactivity

Belvarafenib (HM95573) is a potent pan-RAF inhibitor with antitumor activity and inhibits B-RAF, B-RAFv600E, and C-RAF with IC50 values of 56, 7, and 5 nM.

Smiles

Cc1ccc2c(Nc3cccc(Cl)c3F)nccc2c1NC(=O)c1csc2c(N)ncnc12

Molecular Formula

C23H16ClFN6OS

Molecular Weight

478.93

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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