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BAY-218

Product Specifications

CAS Number

2162982-11-6

Target

AhR, Aryl Hydrocarbon Receptor

Related Pathways

Immunology/Inflammation, Metabolism

Purity

0.9985

Bioactivity

BAY-218 is an aryl hydrocarbon receptor (AHR) antagonist with IC50 of 39.9 nM in the human glioblastoma U87 cell line. BAY-218 inhibition of AhR stimulates pro-inflammatory monocyte and T cell responses in vitro and drives anti-tumor immune responses, leading to reduced tumor growth in vivo.

Smiles

C[C@@H](CO)NC(=O)c1cc(nn(-c2cccc(F)c2)c1=O)-c1ccc(Cl)cc1

Molecular Formula

C20H17ClFN3O3

Molecular Weight

401.82

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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