BAY-218
Product Specifications
CAS Number
2162982-11-6
Target
AhR, Aryl Hydrocarbon Receptor
Related Pathways
Immunology/Inflammation, Metabolism
Purity
0.9985
Bioactivity
BAY-218 is an aryl hydrocarbon receptor (AHR) antagonist with IC50 of 39.9 nM in the human glioblastoma U87 cell line. BAY-218 inhibition of AhR stimulates pro-inflammatory monocyte and T cell responses in vitro and drives anti-tumor immune responses, leading to reduced tumor growth in vivo.
Smiles
C[C@@H](CO)NC(=O)c1cc(nn(-c2cccc(F)c2)c1=O)-c1ccc(Cl)cc1
Molecular Formula
C20H17ClFN3O3
Molecular Weight
401.82
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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