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AK-1

Product Specifications

CAS Number

330461-64-8

Target

Sirtuin

Related Pathways

Chromatin/Epigenetic, DNA Damage/DNA Repair

Purity

0.9944

Bioactivity

AK-1 is a sirtuin 2 (SIRT2) inhibitor (IC50:12.5 μM) .that prevents hippocampal neurodegeneration in Alzheimer's disease models and induces cell cycle arrest in colon carcinoma cells.

Smiles

[O-][N+](=O)c1cccc(NC(=O)c2cccc(c2)S(=O)(=O)N2CCCCCC2)c1

Molecular Formula

C19H21N3O5S

Molecular Weight

403.45

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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