AK-1
Product Specifications
CAS Number
330461-64-8
Target
Sirtuin
Related Pathways
Chromatin/Epigenetic, DNA Damage/DNA Repair
Purity
0.9944
Bioactivity
AK-1 is a sirtuin 2 (SIRT2) inhibitor (IC50:12.5 μM) .that prevents hippocampal neurodegeneration in Alzheimer's disease models and induces cell cycle arrest in colon carcinoma cells.
Smiles
[O-][N+](=O)c1cccc(NC(=O)c2cccc(c2)S(=O)(=O)N2CCCCCC2)c1
Molecular Formula
C19H21N3O5S
Molecular Weight
403.45
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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