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Darovasertib

Product Specifications

CAS Number

1874276-76-2

Target

PKC

Related Pathways

Chromatin/Epigenetic, Cytoskeletal Signaling

Purity

0.9989

Bioactivity

Darovasertib (LXS196) is a potent, selective, and orally active protein kinase C (PKC) inhibitor with IC50 values of 1.9 nM for PKCα, 0.4 nM for PKCθ, and 3.1 μM for GSK3β.

Smiles

CC1(N)CCN(CC1)c1cccnc1NC(=O)c1nc(cnc1N)-c1ncccc1C(F)(F)F

Molecular Formula

C22H23F3N8O

Molecular Weight

472.47

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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