Aurora kinase inhibitor-3

Product Specifications

CAS Number

879127-16-9

Target

Aurora Kinase

Related Pathways

Cell Cycle/Checkpoint|||Chromatin/Epigenetic

Purity

0.9891

Bioactivity

Aurora kinase inhibitor-3 (Aurora Kinase Inhibitor III) is a potent inhibitor of Aurora A kinase (IC50 = 42 nM) .1 It is selective for Aurora A over BMX, BTK, IGF-1R, c-Src, TRKB, SYK, and EGFR.

Smiles

FC(F)(F)c1cccc(Nc2ccnc(Nc3cccc(NC(=O)C4CC4)c3)n2)c1

Molecular Formula

C21H18F3N5O

Molecular Weight

413.4

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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