Imidazole ketone erastin
Product Specifications
CAS Number
1801530-11-9
Target
Ferroptosis
Related Pathways
Apoptosis
Purity
0.9987
Bioactivity
Imidazole ketone erastin (IKE) is an ferroptosis inducer with inhibitory effects on system Xc-cystine/glutamate transporter proteins. Imidazole ketone erastin has antitumor activity and induces glutathione depletion and lipid peroxidation.
Smiles
CC(C)Oc1ccc(cc1-n1c(CN2CCN(CC2)C(=O)COc2ccc(Cl)cc2)nc2ccccc2c1=O)C(=O)Cn1ccnc1
Molecular Formula
C35H35ClN6O5
Molecular Weight
655.14
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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