GNE-6640
Product Specifications
CAS Number
2009273-67-8
Target
DUB
Related Pathways
Ubiquitination, Cell Cycle/Checkpoint, DNA Damage/DNA Repair
Purity
0.9959
Bioactivity
GNE-6640 is a non-covalent inhibitor targeting ubiquitin specific peptidase 7 (USP7), exhibiting IC50 values of 0.75 μM for full-length USP7, 0.43 μM for the USP7 catalytic domain, 20.3 μM for full-length USP43, and 0.23 μM for Ub-MDM2, respectively.
Smiles
CCc1c(cnc(N)c1-c1ccc(O)cc1)-c1ccc2[nH]ncc2c1
Molecular Formula
C20H18N4O
Molecular Weight
330.38
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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