Dbet57

Product Specifications

CAS Number

1883863-52-2

Target

Apoptosis|||Epigenetic Reader Domain|||PROTACs

Related Pathways

PROTAC|||Chromatin/Epigenetic|||Apoptosis

Purity

0.9952

Bioactivity

DBET57 is heterobifunctional degrader of BRD4 based on the PROTAC technology, exhibits significant degradation of BRD4BD1 with a DC50/5h of 500 nM , and inactive on BRD4BD2

Smiles

CC=1C2=C(N3C([C@H](CC(NCCNC4=C5C(C(=O)N(C5=O)C6C(=O)NC(=O)CC6)=CC=C4)=O)N=C2C7=CC=C(Cl)C=C7)=NN=C3C)SC1C

Molecular Formula

C34H31ClN8O5S

Molecular Weight

699.18

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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