ARV-825

Product Specifications

CAS Number

1818885-28-7

Target

Epigenetic Reader Domain, PROTACs

Related Pathways

Chromatin/Epigenetic, PROTAC

Purity

0.98

Bioactivity

ARV-825, a heterobifunctional PROTAC (Proteolysis Targeting Chimera) that recruits BRD4 to the E3 ubiquitin ligase cereblon leading to fast, efficient, and prolonged degradation of BRD4 in all BL cell lines tested.

Smiles

CC=1C2=C(N3C([C@H](CC(NC4=CC=C(OCCOCCOCCOCCNC5=C6C(C(=O)N(C6=O)C7C(=O)NC(=O)CC7)=CC=C5)C=C4)=O)N=C2C8=CC=C(Cl)C=C8)=NN=C3C)SC1C

Molecular Formula

C46H47ClN8O9S

Molecular Weight

923.43

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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