BI-3802
Product Specifications
CAS Number
2166387-65-9
Target
Bcl-2 Family|||Molecular Glues|||Bcl-6
Related Pathways
PROTAC|||Apoptosis|||Immunology/Inflammation
Purity
0.9948
Bioactivity
BI-3802, a highly potent BCL6 degrader, targets and inhibits the Bric-à-brac (BTB) domain of BCL6, exhibiting an IC50 value of ?3 nM. It induces polymerization of BCL6 and facilitates its degradation in a manner dependent on the E3 ligase SIAH1, demonstrating notable antitumor activity[1][2].
Smiles
CNC(=O)COc1cc2cc(Nc3nc(ncc3Cl)N3C[C@@H](C)C[C@@H](C)C3)ccc2n(C)c1=O
Molecular Formula
C24H29ClN6O3
Molecular Weight
484.98
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS7209405-01 48 Well
Monkey Coiled-coil-helix-coiled-coil-helix domain-containing protein 5 (CHCHD5) ELISA Kit
Ask
View Details 
MBS7209405-02 96 Well
Monkey Coiled-coil-helix-coiled-coil-helix domain-containing protein 5 (CHCHD5) ELISA Kit
Ask
View Details MBS7209405-03 5x 96 Well
Monkey Coiled-coil-helix-coiled-coil-helix domain-containing protein 5 (CHCHD5) ELISA Kit
Ask
View Details 
MBS7209405-04 10x 96 Well
Monkey Coiled-coil-helix-coiled-coil-helix domain-containing protein 5 (CHCHD5) ELISA Kit
Ask
View Details