BI-1347

Product Specifications

CAS Number

2163056-91-3

Target

CDK

Related Pathways

Cell Cycle/Checkpoint

Purity

0.9963

Bioactivity

BI-1347 is a potent, selective inhibitor of CDK8/cyclinC (IC50: 1 nM) . It shows tumor growth inhibition in an in vivo xenograft model.

Smiles

CN(C)C(=O)Cn1cc(cn1)-c1ccc(cc1)-c1cncc2ccccc12

Molecular Formula

C22H20N4O

Molecular Weight

356.42

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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