BMS 599626 2HCl
Product Specifications
CAS Number
1781932-33-9
Target
HER
Related Pathways
Angiogenesis, Tyrosine Kinase/Adaptors, JAK/STAT signaling
Purity
0.9994
Bioactivity
BMS 599626 2HCl (873837-23-1 (HCl) ) (AC480 dihydrochloride) is a selective inhibitor of HER1 and HER2 (IC50s: 20 nM and 30 nM), ~8-fold less potent to HER4, >100-fold to Lck, VEGFR2, c-Kit, MET, etc.
Smiles
O=C(OC[C@@H]1COCCN1)NC2=CN3C(C(NC4=CC=C(N(N=C5)CC6=CC(F)=CC=C6)C5=C4)=NC=N3)=C2C.Cl.Cl
Molecular Formula
C27H29FN8O3Cl2
Molecular Weight
603.48
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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