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BMS-599626 Hydrochloride

Product Specifications

CAS Number

873837-23-1

Target

EGFR, HER

Related Pathways

JAK/STAT signaling, Angiogenesis, Tyrosine Kinase/Adaptors

Purity

>99.99%

Bioactivity

BMS-599626 Hydrochloride (AC480 Hydrochloride) is an orally bioavailable inhibitor of the HER1, HER2, and HER4 tyrosine kinases (IC50 = 22, 32, and 190 nM, respectively) with potential antineoplastic activity, inhibiting the proliferation of tumor cells that overexpress these receptors.

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Cl.Cc1c(NC(=O)OC[C@@H]2COCCN2)cn2ncnc(Nc3ccc4n(Cc5cccc(F)c5)ncc4c3)c12

Molecular Formula

C27H28ClFN8O3

Molecular Weight

567.01

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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