BMS-599626 Hydrochloride
Product Specifications
CAS Number
873837-23-1
Target
EGFR, HER
Related Pathways
JAK/STAT signaling, Angiogenesis, Tyrosine Kinase/Adaptors
Purity
>99.99%
Bioactivity
BMS-599626 Hydrochloride (AC480 Hydrochloride) is an orally bioavailable inhibitor of the HER1, HER2, and HER4 tyrosine kinases (IC50 = 22, 32, and 190 nM, respectively) with potential antineoplastic activity, inhibiting the proliferation of tumor cells that overexpress these receptors.
Smiles
Cl.Cc1c(NC(=O)OC[C@@H]2COCCN2)cn2ncnc(Nc3ccc4n(Cc5cccc(F)c5)ncc4c3)c12
Molecular Formula
C27H28ClFN8O3
Molecular Weight
567.01
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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