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Sparsentan

Product Specifications

CAS Number

254740-64-2

Target

RAAS, Endothelin Receptor

Related Pathways

Endocrinology/Hormones, GPCR/G Protein

Purity

0.9881

Bioactivity

Sparsentan (DARA-a) is a first-in-class orally active and highly potent dual endothelin A and angiotensin II receptor antagonist (Ki of 9.3 and 0.8 nM, respectively)

Smiles

CCCCC1=NC2(CCCC2)C(=O)N1Cc1ccc(c(COCC)c1)-c1ccccc1S(=O)(=O)Nc1noc(C)c1C

Molecular Formula

C32H40N4O5S

Molecular Weight

592.75

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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