IWP-O1
Product Specifications
CAS Number
2074607-48-8
Target
Porcupine|||Wnt/beta-catenin
Related Pathways
Stem Cells|||Cytoskeletal Signaling
Purity
0.9998
Bioactivity
IWP-O1, a highly potent Porcupine (Porcn) inhibitor (EC50: 80 pM), effectively suppresses the phosphorylation of Dvl2/3 and LRP6 in HeLa cells.
Smiles
O=C(Cn1nnc(c1-c1ccccc1)-c1ccncc1)Nc1ccc(cn1)-c1ccccc1
Molecular Formula
C26H20N6O
Molecular Weight
432.48
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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