IWP-O1

Product Specifications

CAS Number

2074607-48-8

Target

Porcupine|||Wnt/beta-catenin

Related Pathways

Stem Cells|||Cytoskeletal Signaling

Purity

0.9998

Bioactivity

IWP-O1, a highly potent Porcupine (Porcn) inhibitor (EC50: 80 pM), effectively suppresses the phosphorylation of Dvl2/3 and LRP6 in HeLa cells.

Smiles

O=C(Cn1nnc(c1-c1ccccc1)-c1ccncc1)Nc1ccc(cn1)-c1ccccc1

Molecular Formula

C26H20N6O

Molecular Weight

432.48

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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