Cridanimod sodium
Product Specifications
CAS Number
58880-43-6
Target
Others, IFNAR
Related Pathways
Others, Immunology/Inflammation
Bioactivity
Cridanimod can increase progesterone receptor (PR) expression, with potential antineoplastic adjuvant activity. Cridanimod is able to induce the expression of PR in endometrial cancer. In combination with a progestin, cancer cells could be eradicated through increased PR-mediated signaling, leading to an inhibition of luteinizing hormone release from the pituitary gland, via a negative feedback mechanism, and, eventually, an inhibition of estrogen released from the ovaries.
Smiles
[Na+].[O-]C(=O)CN1C2=C(C=CC=C2)C(=O)C2=C1C=CC=C2
Molecular Formula
C15H11NNaO3
Molecular Weight
276.24
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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