3-Chloro-L-Tyrosine
Product Specifications
CAS Number
7423-93-0
Target
Endogenous Metabolite|||Glutathione Peroxidase
Related Pathways
Metabolism
Purity
0.9895
Bioactivity
3-Chloro-L-Tyrosine (Chlorotyrosine), a specific marker of myeloperoxidase-catalyzed oxidation, is markedly elevated in low-density lipoprotein isolated from human atherosclerotic intima. In particular, myeloperoxidase halogenates tyrosine residues in plasma proteins and generates 3-chlorotyrosine (CY) . The detection of free chlorotyrosine in blood or urine arises from the degradation of these chlorinated proteins. CY concentrations may be useful for monitoring the activation of neutrophils in asthmatic patients.
Smiles
N[C@@H](Cc1ccc(O)c(Cl)c1)C(O)=O
Molecular Formula
C9H10ClNO3
Molecular Weight
215.63
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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