Cabozantinib hydrochloride
Product Specifications
CAS Number
1817759-42-4
Target
C-Kit, FLT, Apoptosis, VEGFR, c-Met/HGFR, ROR, TAM Receptor
Related Pathways
Tyrosine Kinase/Adaptors, Apoptosis, Metabolism, Angiogenesis
Purity
0.9997
Bioactivity
Cabozantinib hydrochloride (XL184) is a potent pan-tyrosine kinases inhibitor that inhibits VEGFR2, c-Met, Kit, Axl, and Flt4 (IC50s: 0.035, 1.3, 4.6, 7 and 6 nM) .
Smiles
Cl.COc1cc2nccc(Oc3ccc(NC(=O)C4(CC4)C(=O)Nc4ccc(F)cc4)cc3)c2cc1OC
Molecular Formula
C28H25ClFN3O5
Molecular Weight
537.96
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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