What is the catalog number for Avapritinib?

The catalog number for Avapritinib is T5109.

What sizes are available for Avapritinib?

Avapritinib is available in the following size(s): 1 mg, 5 mg, 10 mg, 1 mL - 10 mM (in DMSO), 25 mg, 50 mg, 100 mg, 200 mg.

How many pack sizes does Avapritinib come in?

Avapritinib is available in 8 different pack sizes.

Is Avapritinib in stock?

Avapritinib is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Avapritinib?

Avapritinib is manufactured by Molfinity.

What is the estimated delivery time for Avapritinib?

Estimated delivery time for Avapritinib is approximately 10 business day(s), depending on your location.

Avapritinib

Product Specifications

CAS Number

1703793-34-3

Target

PDGFR, c-Kit

Related Pathways

Tyrosine Kinase/Adaptors, Angiogenesis

Purity

0.997

Bioactivity

Avapritinib (BLU-285) is a selective, highly potent, and orally active inhibitor of KIT and PDGFRA activation loop mutant kinases, targeting KIT D816V (IC50:0.27 nM) and PDGFRA D842V (IC50:0.24 nM), and attenuates the transport functions of ABCB1 and ABCG2. It binds to the active conformation of the kinases and exhibits antitumor activity.