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Gefapixant

Product Specifications

CAS Number

1015787-98-0

Target

P2X Receptor

Related Pathways

Membrane transporter/Ion channel, Neuroscience

Purity

0.9972

Bioactivity

Gefapixant (AF219) is a P2X3 receptor (P2X3R) antagonist with IC50 of ~30 nM at recombinant hP2X3 homotrimers and 100-250 nM at hP2X2/3 heterotrimeric receptors.

Smiles

COc1cc(C(C)C)c(Oc2cnc(N)nc2N)cc1S(N)(=O)=O

Molecular Formula

C14H19N5O4S

Molecular Weight

353.4

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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