Gefapixant
Product Specifications
CAS Number
1015787-98-0
Target
P2X Receptor
Related Pathways
Membrane transporter/Ion channel|||Neuroscience
Purity
0.9972
Bioactivity
Gefapixant (AF219) is a P2X3 receptor (P2X3R) antagonist with IC50 of ~30 nM at recombinant hP2X3 homotrimers and 100-250 nM at hP2X2/3 heterotrimeric receptors.
Smiles
COc1cc(C(C)C)c(Oc2cnc(N)nc2N)cc1S(N)(=O)=O
Molecular Formula
C14H19N5O4S
Molecular Weight
353.4
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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