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Pamiparib

Product Specifications

CAS Number

1446261-44-4

Target

PARP

Related Pathways

DNA Damage/DNA Repair, Chromatin/Epigenetic

Purity

0.9969

Bioactivity

Pamiparib (BGB-290) is an orally active, potent, highly selective PARP inhibitor with IC50 values of 0.9 nM for PARP1 and 0.5 nM for PARP2. It exhibits strong PARP trapping, has the capability to penetrate the brain, and is used for researching various cancers, including solid tumors.

Smiles

C[C@]12CCCN1Cc1n[nH]c(=O)c3cc(F)cc4[nH]c2c1c34

Molecular Formula

C16H15FN4O

Molecular Weight

298.31

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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