Pamiparib
Product Specifications
CAS Number
1446261-44-4
Target
PARP
Related Pathways
DNA Damage/DNA Repair|||Chromatin/Epigenetic
Purity
0.9969
Bioactivity
Pamiparib (BGB-290) is an orally active, potent, highly selective PARP inhibitor with IC50 values of 0.9 nM for PARP1 and 0.5 nM for PARP2. It exhibits strong PARP trapping, has the capability to penetrate the brain, and is used for researching various cancers, including solid tumors.
Smiles
C[C@]12CCCN1Cc1n[nH]c(=O)c3cc(F)cc4[nH]c2c1c34
Molecular Formula
C16H15FN4O
Molecular Weight
298.31
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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