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Futibatinib

Product Specifications

CAS Number

1448169-71-8

Target

FGFR

Related Pathways

Tyrosine Kinase/Adaptors, Angiogenesis

Purity

0.9944

Bioactivity

Futibatinib (TAS-120) is an orally active, potent, selective, highly bioavailable, and irreversible FGFR inhibitor with IC50 values ​​of 3.9, 1.3, 1.6, and 8.3 nM for FGFR1, FGFR2, FGFR3, and FGFR4, respectively. [2]

Smiles

COc1cc(OC)cc(c1)C#Cc1nn([C@H]2CCN(C2)C(=O)C=C)c2ncnc(N)c12

Molecular Formula

C22H22N6O3

Molecular Weight

418.45

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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