Tofogliflozin (hydrate)

Product Specifications

CAS Number

1201913-82-7

Target

ROS|||SGLT|||Reactive Oxygen Species

Related Pathways

NF-?B|||Immunology/Inflammation|||GPCR/G Protein|||Metabolism

Purity

0.9878

Bioactivity

Tofogliflozin hydrate (CSG-452 hydrate) is a potent and highly specific inhibitor of SGLT2, with an IC50 of 2.9 nM and Ki values of 2.9 nM, 14.9 nM, and 6.4 nM for human, rat, and mouse SGLT2, respectively.

Smiles

O.CCc1ccc(Cc2ccc3CO[C@]4(O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)c3c2)cc1

Molecular Formula

C22H28O7

Molecular Weight

404.45

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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