Tofogliflozin (hydrate)
Product Specifications
CAS Number
1201913-82-7
Target
ROS|||SGLT|||Reactive Oxygen Species
Related Pathways
NF-?B|||Immunology/Inflammation|||GPCR/G Protein|||Metabolism
Purity
0.9878
Bioactivity
Tofogliflozin hydrate (CSG-452 hydrate) is a potent and highly specific inhibitor of SGLT2, with an IC50 of 2.9 nM and Ki values of 2.9 nM, 14.9 nM, and 6.4 nM for human, rat, and mouse SGLT2, respectively.
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O.CCc1ccc(Cc2ccc3CO[C@]4(O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)c3c2)cc1
Molecular Formula
C22H28O7
Molecular Weight
404.45
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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