HIF-2α-IN-4
Product Specifications
CAS Number
882268-69-1
Target
HIF/HIF Prolyl-Hydroxylase
Related Pathways
Chromatin/Epigenetic, Metabolism
Purity
≥98%
Bioactivity
HIF-2a translation inhibitor is a potent HIF-2α translation inhibitor with IC50=5 μM that inhibits constitutive and hypoxia-induced HIF-2α protein expression. Among them, HIF-2α-IN-4 associates the 5'UTR iron response element with oxygen sensing.
Smiles
COC(=O)c1sccc1N\N=C(/C#N)S(C)(=O)=O
Molecular Formula
C9H9N3O4S2
Molecular Weight
287.32
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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