Hippeastrine (hydrobromide)

Product Specifications

CAS Number

[22352-41-6]

UNSPSC Description

Hippeastrine hydrobromide is an active alkaloid that exhibits a good dose-dependent inhibitory effect on topoisomerase I (Top I) with an IC50 of 7.25?μg/mL. Hippeastrine hydrobromide exhibits antiproliferative and anticancer activities[1].

Target Antigen

Topoisomerase

Type

Natural Products

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

cancer

Assay Protocol

https://www.medchemexpress.com/hippeastrine-hydrobromide.html

Smiles

O=C1O[C@]([H])([C@H](C=C2CCN(C32)C)O)[C@@]3([H])C4=CC5=C(OCO5)C=C14.Br

Molecular Weight

396.23

References & Citations

[1]Chen GL, et al. Antiproliferative activities of Amaryllidaceae alkaloids from Lycoris radiata targeting DNA topoisomerase I. Sci Rep. 2016;6:38284. Published 2016 Dec 6.