Licochalcone B
Product Specifications
CAS Number
58749-23-8
Target
Apoptosis, NOD-like Receptor (NLR), Beta Amyloid
Related Pathways
Immunology/Inflammation, Apoptosis, Neuroscience
Purity
0.9993
Bioactivity
1. Licochalcone B (LCB) inhibits the proliferation of human malignant bladder cancer cell lines (T24 and EJ) in vitro and antitumor activity in vivo in MB49 (murine bladder cancer cell line) tumor model. 2. LCB and Licochalcone D (LCD) significantly reduced the LPS-induced production of NO, TNFalpha and MCP-1. 3. A novel LCB derivative compound: (E) -3- (3, 4-dihydroxy-2-methoxyphenyl) -1- (2, 4-dihydroxyphenyl) prop-2-en-1-one inhibits inflammatory reactions in macrophages and protects mice from endotoxin shock.
Smiles
COc1c(O)c(O)ccc1\C=C\C(=O)c1ccc(O)cc1
Molecular Formula
C16H14O5
Molecular Weight
286.28
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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