Hinokiflavone
Product Specifications
CAS Number
19202-36-9
Target
Apoptosis, Bcl-2 Family, Protease, E1/E2/E3 Enzyme, MMP
Related Pathways
Ubiquitination, Apoptosis, Proteases/Proteasome
Purity
0.9867
Bioactivity
Hinokiflavone, a novel modulator of pre-mRNA splicing activity both in vitro and in cellulo, inhibits the assembly of the spliceosome, particularly blocking the formation of the B complex. Additionally, it acts as a SUMO protease inhibitor by impeding the activity of sentrin-specific protease 1 (SENP1) . Hinokiflavone also demonstrates significant cytotoxicity, including the inhibition of MMP-9.
Smiles
Oc1ccc(cc1)-c1cc(=O)c2c(O)c(Oc3ccc(cc3)-c3cc(=O)c4c(O)cc(O)cc4o3)c(O)cc2o1
Molecular Formula
C30H18O10
Molecular Weight
538.46
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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