Hinokiflavone
Product Specifications
CAS Number
19202-36-9
Target
Apoptosis|||Bcl-2 Family|||Protease|||E1/E2/E3 Enzyme|||MMP
Related Pathways
Ubiquitination|||Apoptosis|||Proteases/Proteasome
Purity
0.9867
Bioactivity
Hinokiflavone, a novel modulator of pre-mRNA splicing activity both in vitro and in cellulo, inhibits the assembly of the spliceosome, particularly blocking the formation of the B complex. Additionally, it acts as a SUMO protease inhibitor by impeding the activity of sentrin-specific protease 1 (SENP1) . Hinokiflavone also demonstrates significant cytotoxicity, including the inhibition of MMP-9.
Smiles
Oc1ccc(cc1)-c1cc(=O)c2c(O)c(Oc3ccc(cc3)-c3cc(=O)c4c(O)cc(O)cc4o3)c(O)cc2o1
Molecular Formula
C30H18O10
Molecular Weight
538.46
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS6216326-01 0.1 mL
CHUK (conserved Helix-loop-Helix ubiquitous Kinase, IKBKA, IKK-alpha, IKK1, IKKA, NFKBIKA, TCF16) (MaxLight 550)
Ask
View Details MBS6216326-02 5x 0.1 mL
CHUK (conserved Helix-loop-Helix ubiquitous Kinase, IKBKA, IKK-alpha, IKK1, IKKA, NFKBIKA, TCF16) (MaxLight 550)
Ask
View Details 
C7910-16E 200 µL
CKBB, NT (Creatine Kinase B-type, Creatine Kinase B Chain, B-CK, CKB)
Ask
View Details