Telocinobufagin
Product Specifications
CAS Number
472-26-4
Target
PI3K, Others, Akt, Apoptosis, ATPase, PLK, STAT, JAK, mTOR
Related Pathways
Stem Cells, JAK/STAT signaling, PI3K/Akt/mTOR signaling, Chromatin/Epigenetic, Apoptosis, Cytoskeletal Signaling, Tyrosine Kinase/Adaptors, Others, Cell Cycle/Checkpoint, Membrane transporter/Ion channel, Angiogenesis
Purity
0.9974
Bioactivity
1. Telocinobufagin (Telobufotoxin) is the major endogenous digitalis-like factor. 2. Telocinobufagin significantly decreases the bacterial burdens in the spleen and prolongs the survival time of FIST-immunized mice challenged with live S. typhimurium. 3. Telocinobufagin has immunomodulatory activity, can enhance a Th1 immune response to control intracellular infections, could be developed as a novel immunotherapeutic agent to treat cancer and other immune-mediated diseases.
Smiles
[H][C@@]12CC[C@]3(O)C[C@@H](O)CC[C@]3(C)[C@@]1([H])CC[C@]1(C)[C@H](CC[C@]21O)c1ccc(=O)oc1
Molecular Formula
C24H34O5
Molecular Weight
402.52
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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