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Paraxanthine

Product Specifications

CAS Number

611-59-6

Target

Endogenous Metabolite, Drug Metabolite

Related Pathways

Metabolism

Purity

0.9999

Bioactivity

Paraxanthine (1,7-dimethylxanthine) is a metabolite of caffeine (sc-202514) which functions as an adenosine receptor ligand and a PARP-1 inhibitor in pulmonary epithelial cells. Studies suggest that Paraxanthine is structurally similar to caffeine and possibly mediates the physiological effects of caffeine. Also Paraxanthine acts as a competitive phosphodiesterase inhibitor, which increases intracellular cAMP, activates PKA, inhibits TNF-α and leukotriene synthesis. In addition, Paraxanthine acts as a Na+/K+ ATPase enzymatic effector.

Smiles

Cn1cnc2[nH]c(=O)n(C)c(=O)c12

Molecular Formula

C7H8N4O2

Molecular Weight

180.16

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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